I don't really pay attention to TKO. I think it's a made up formula that's kind of widgety. I look at energy when I do my ballistic table. In the past some gov lab guy with a BGH determined that 250-350ish ftlbs will kill a human pretty much dead so we would always use that as a guideline. At 800m with the standard data, 175gr GMM/AB39/M118LR has 683 ftlbs of energy while the 140gr SOF ammo (140gr Berger Hybrid) with standard data has 809 ftlbs of energy. Bullet diameter and all that extra mumbo jumbo means nothing except in the flight ballistics. So a 140gr Berger Hybrid will kill something a little more dead than the 308 SMK it's replacing and it's way more accurate for a much longer range. Now, shorter barrels, environmentals, etc that reduces velocity will change those numbers but the .264 140gr will always outperform the 175grSMK as long as it's going at the speed it needs to.
WRT to the 6.8x51, that's what the regular Army is going to for "front line" soldiers. It's not a regular 6.8. It 80K PSI and going 3000FPS out of a 16" barrel. My buddy described it as shooting "a bag full of dildos falling off a truck". I guess it's about as accurate as a bowling ball too. They all love the machinegun though. The M4/M16 isn't going anywhere anytime soon.
The 140gr 6.5CM Bryan is talking about is for USSOCOM for the DMR and Sniper gas guns.
None of this is professional or medical advice, only my opinion.